Mediterranean Cruises from the UK

Cruise from the UK to the Mediterranean, one of the most popular cruise destinations. Discover Spain’s architectural cities, explore the jewels of the glamorous French Riviera, or admire Renaissance treasures along the Italian coast. Cruises can also visit the stunning Croatian coast including UNESCO-listed Dubrovnik, and sail the waters of the Adriatic to the pretty Greek islands with their whitewashed villages.

  • Mykonos
  • Venice Gondolas
  • Split
  • Dubrovnik
  • Athens

Mediterranean Cruises

Mediterranean

P&O Cruises
Mediterranean on Arcadia
19 Nights
Departs 10 Jun 2026
from Southampton
  • £1,551pp

Southampton, Lisbon, Alicante, Livorno, Civitavecchia, Cartagena, Casablanca, Tangier, Vigo

7 Night Spain & Portugal Cruise

Royal Caribbean International
7 Night Spain & Portugal Cruise on Liberty of the Seas
7 Nights
Departs 14 Jun 2026
from Southampton
  • £978pp
  • £2,063pp

Southampton, La Coruña, Lisbon, Vigo

21-Day Norwegian Fjords & Mediterranean Adventurer

Princess Cruises
21-Day Norwegian Fjords & Mediterranean Adventurer on Sky Princess
21 Nights
Departs 11 Jul 2026
from Southampton
  • £2,684pp
  • £4,060pp

Southampton, Bergen, Skjolden, Olden, Stavanger, Cádiz, Barcelona, La Seyne-sur-Mer, Livorno, Civitavecchia, Ajaccio, Corsica

Spain

P&O Cruises
Spain on Arcadia
7 Nights
Departs 13 Jul 2026
from Southampton
  • £950pp
  • £969pp
  • £1,309pp
  • £2,133pp

Southampton, La Coruña, Gijón, Santander, Saint Peter Port

Mediterranean

P&O Cruises
Mediterranean on Britannia
14 Nights
Departs 17 Jul 2026
from Southampton
  • £1,309pp
  • £1,600pp

Southampton, Cádiz, Ibiza, Cagliari, Palma de Mallorca, Cartagena, Gibraltar

14-Day Mediterranean Adventurer

Princess Cruises
14-Day Mediterranean Adventurer on Sky Princess
14 Nights
Departs 18 Jul 2026
from Southampton
  • £1,658pp
  • £1,963pp
  • £2,169pp

Southampton, Cádiz, Barcelona, La Seyne-sur-Mer, Livorno, Civitavecchia, Ajaccio, Corsica

Mediterranean

P&O Cruises
Mediterranean on Britannia
14 Nights
Departs 31 Jul 2026
from Southampton
  • £1,289pp
  • £1,600pp
  • £3,879pp

Southampton, Cádiz, Ibiza, Cagliari, Palma de Mallorca, Cartagena, Gibraltar

Spain And France

P&O Cruises
Spain And France on Ventura
7 Nights
Departs 01 Aug 2026
from Southampton
  • £853pp
  • £853pp
  • £1,018pp

Southampton, La Coruña, Gijón, Santander, Cherbourg

European Explorer

Oceania Cruises
European Explorer on Oceania Sirena
22 Nights
Departs 05 Aug 2026
from Southampton
  • £5,749pp
  • £9,449pp
  • £11,609pp

Southampton, Le Verdon-sur-Mer, Saint-Jean-de-Luz, Santander, Ferrol, Porto, Lisbon, Cádiz (Spain), Málaga, Almería, Alicante, Barcelona, Palermo, Siracuse, Sicily, Argostoli, Gythio, Páros, Piraeus, Kusadasi, Bozcaada, Istanbul

Spain And Portugal

P&O Cruises
Spain And Portugal on Ventura
14 Nights
Departs 08 Aug 2026
from Southampton
  • £1,115pp
  • £1,260pp
  • £1,551pp

Southampton, Santander, Gijón, Ferrol, Funchal, Madeira, Lisbon, Vigo

Spain And France

P&O Cruises
Spain And France on Iona
7 Nights
Departs 08 Aug 2026
from Southampton
  • £775pp
  • £1,018pp
  • £1,095pp
  • £1,600pp

Southampton, Getxo, La Coruña, Vigo, Cherbourg

14-Day Spain, France & Portugal with Total Solar Eclipse

Princess Cruises
14-Day Spain, France & Portugal with Total Solar Eclipse on Sky Princess
14 Nights
Departs 08 Aug 2026
from Southampton
  • £1,932pp
  • £2,280pp
  • £3,670pp

Southampton, Cherbourg, Bilbao, Total Solar Eclipse 2026, Málaga, Cartagena, Gibraltar, Lisbon, La Coruña

About Mediterranean Cruises

Your cruise from the UK reaches the Mediterranean Sea at Gibraltar, passing through the narrow straits separating Europe from North Africa. Noted for its famous rock and its colony of apes, Gibraltar has a very British feel.

Along the coast of Spain call at flamboyant Barcelona, with its unfinished symbol of the Sagrada Familia and the amazing shapes of the Gaudi sculptures and buildings. In complete contrast are the beaches and towns of Mallorca and Ibiza.

For that touch of glamour, include Cannes, St Tropez or Monte Carlo on your cruise itinerary. These smart French resorts on the French Riviera have their own unique appeal.

Call at Livorno on the Italian coast, gateway to see some of the finest works of art and architecture in the world in Pisa and Florence. Other popular ports are Civitavecchia, just a stone’s throw from the ancient city of Rome, and Naples, close to the amazingly preserved ruins of Pompeii.

Cruise the Adriatic Sea and call at the Greek island of Corfu, sail into beautiful Kotor Bay in Montenegro, then visit the ancient Croatian walled town of Dubrovnik before reaching the unique canal city of Venice. See the major sights including St Mark's Cathedral and the Doge's Palace.

Longer cruises from the UK may visit the beautiful Greek islands of lively Mykonos, picture-postcard Santorini and historic Rhodes.